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Chemotherapy Side Effects

Scientists have made a great deal of progress in developing therapies to help prevent and manage the side effects of chemotherapy. Newer supportive care treatments have led to vast improvements in the management of symptoms associated with cancer treatment. Some people don't experience side effects at all, and you are unlikely to experience all the side effects you read about below. Although chemotherapy is designed to treat cancer cells; unfortunately, it often affects parts of your body not directly affected by the cancer itself. This undesired result is referred to as a complication of treatment, or a side effect.

Side effects may be acute (short-term), chronic (long-term), or permanent. Side effects may cause inconvenience, discomfort, and even death.

Additionally, certain side effects may prevent doctors from delivering the prescribed dose of chemotherapy at the specific time and schedule of the treatment plan.11, 36, 37 In certain cancers, the expected outcome from chemotherapy is based on delivering the full chemotherapy dose on schedule and so, it is important to understand chemotherapy cycles and schedules.

Side effects from chemotherapy can include pain, diarrhea, constipation, mouth sores, hair loss, nausea and vomiting, as well as blood-related side effects. In this section, you can learn more about the importance of diagnosing and monitoring blood-related side effects. These may include low number of infection fighting white blood cell count (neutropenia), low red blood cell count (anemia), and low platelet count (thrombocytopenia).

CBC and Related Side Effects

The CBC, or complete blood count, helps your doctor look for side effects of chemotherapy, which include changes in the three types of cells in your blood. Because chemotherapy kills fast-growing blood cells as well as cancer cells, side effects involving your blood are an expected result of chemotherapy. Your first step in understanding blood-related side effects is knowing CBC, or your complete blood count.

Side effects involving blood include the following:

Neutropenia

Neutropenia (new-troh-PEE-nee-ah) is the scientific name for a low infection-fighting white blood cell count. A low white blood cell count may leave your body vulnerable to infection and too weak to receive chemotherapy at the full dose on schedule.11, 36, 37 This could lead your doctor to delay your current treatment or reduce your doses until your count reaches sufficient levels. Infection can lead to hospitalization. To help reduce the risk of treatment delays due to blood-related side effects, find out more about the risks associated with low white cell blood count.

Anemia

Anemia (ah-NEE-mee-ah) is the scientific name for a low red blood cell count. Red blood cells (RBCs) contain hemoglobin (HEE-moh-glow-bin), or Hb, a protein that carries oxygen from the lungs to the body’s muscles and organs. Oxygen is critical to the health of your tissues and organs. If you are diagnosed with anemia while receiving chemotherapy to treat certain types of cancer, there are multiple treatment options. Two of these options are red blood cell transfusions and erythropoiesis-stimulating agents (ESAs).

Thrombocytopenia

Thrombocytopenia (throm-boh-sy-toh-PEE-nee-ah) is the scientific name for a low platelet count. A low platelet count may cause you to experience bruising or excessive bleeding. Learn more about the risks of low platelet count.



All of these side effects may be related to your chemotherapy. All are diagnosed through your CBC test. You can manage them to help reduce the possibility that they will compromise your treatment. A journal provides a place for you to keep track of your blood counts throughout your chemotherapy, and is one of the Tools for Organizing Your Cancer Information.

In addition to blood-related side effects, chemotherapy can result in other side effects that can interfere with treatment if not managed properly. Learn more about other types of chemotherapy side effects.

Sometimes side effects signal a serious problem. Find out when to call your doctor about chemotherapy side effects.



UNDERSTANDING CANCER
TREATING CANCER WITH CHEMOTHERAPY
CHEMOTHERAPY SIDE EFFECTS
TREATING CANCER IN OTHER WAYS
TRACKING YOUR TEST RESULTS
UNDERSTANDING INSURANCE AND TAX ISSUES: INSURANCE TIPS
WEB RESOURCES AND ORGANIZATIONS
TOOLS FOR ORGANIZING YOUR CANCER INFORMATION
FOR CAREGIVERS
GLOSSARY OF CANCER TERMS
REGISTER FOR PROGRAMS
FOR HEALTHCARE PROFESSIONALS
Treat anemia caused by chemotherapy used to treat certain types of cancer. Learn more.
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